Praziquantel ( Prazi ) is the preeminent treatment for flukes. It is by far the most gentle, yet effective treatment for flukes available to our hobby. The real bonus with Prazi is that when you treat for flukes, it also rids the fish of any internal parasites or worms of the same family.
Prazi is extremely effective for the treatment of external flukes, liver flukes, internal parasites, and internal worms in koi, goldfish, and tropical fish. It is a one time treatment, and because it is so gentle, it does NOT require any water changes after treatment. You do NOT need to bypass your biofilter during treatments. Prazi also will work with any amount of salt in the pond, and it is not water temperature dependent.
It is also 100% legal. (unlike Supaverm) Prazi has been sought after for years as the fluke treatment of choice, but has not been unavailable in our hobby.... Until NOW!
As a preventative, we recommend treating once a year in early Spring.